Wednesday, February 24, 2010

Deßate Topic :: Stem Cells for Cloning

Should humans use stem cells to clone for necessary genes?


The use of embryonic stem cells in laboratory research has been a hot topic over the years. Some people will argue that it can help rid of certain diseases and genetic disorders, while others will argue that it is unethical and has too low of a success rate to be trialed on over and over again. I support the latter of the two arguments. I believe stem cell cloning should be stopped as soon as possible.


A quick overview of exactly how the process of cloning, or somatic cell nuclear transfer, works. Essentially what happens is a female egg cell has its nucleus removed and replaced by the nucleus of a regular body cell, aka a somatic cell. The somatic cell's nucleus is practically re-programmed to the egg cell's body, and the cell will now start dividing. After there are a couple hundred haploid cells, the new body is an embryo with a genetic makeup that is almost identical to that of the original somatic cell.


Why is this such a bad thing if it can help researchers cure diseases?


  • The chances that the embryo will make it to the adult stage is extremely slim. Dolly the Sheep, for instance, was a clone. She was modified along with 277 other sheep cells. Only 29 of those cells made to the embryonic stages Of those 29 embryos, only 3 made it to the stage of birth. Dolly was the only one to make it to the adult stage. Once an adult sheep, Dolly physically matured to fast and died of a cellular disorder at age 6.
  • It is unethical to take a human egg, which is a possible human life, turn it into an embryo, another possible human life, genetically modify it and test it to see if you can cure diseases. It's similar to setting up a lab of humans and testing harmful chemicals on them.
  • An eventual overuse of reproductive cloning could replace natural sexual reproduction altogether, then everything would be genetically modified. Having a world full of genetically modified individuals would alter the way God and nature intended one to be.
Thanks for your time.


Debate Reflection: I think the debate went fairly well. Some of the questions caught me off guard, to the point that I had to kind of wing it. But overall, I felt confident with what I was talking about. I actually enjoyed doing this research. Honestly, I like doing debates and speaches. I like to fight for what I believe in, even though I actually don't believe in the stopping of stem cell cloning.


BiBLiOGRAPHY

Manske, Magnus. "Somatic cell nuclear transfer." Wikipedia. 2003. Web. http://en.wikipedia.org/wiki/Somatic_cell_nuclear_transfer.

Stem Cells: The Ethics of Cloning. Films for the Humanities & Science: 2009, Film.

Hanna, Kathi. "Cloning/Embryonic Stem Cells." Genome. Apr 2006. Web. 24 Feb 2010. http://www.genome.gov/10004765.

Tuesday, February 23, 2010

Genetic Monster :: Genetic Traits

I have several choices as to how to arrange these genetic traits. These are the ones I can choose from.

Single Allele:

Multiple Allele:

Sex Linked:

Incomplete:

Codominant:

Now how will I actually arrange my genetic monster? I narrowed it down to two. I can either do...

1. Ocho Nueve

2. Tres Quatro

Tres Quatro's a beast and all, but I'll have to go with Ocho Nueve.

Monday, February 22, 2010

Ocho Nueve :: The Genetic Monster







This is my little friend Ocho Nueve. I genetically modified him in my laboratory.

Antenna Types. (Single Allele Trait)
Possible Phenotypes: Straight (Dominant) vs. Curved (Recessive)
Possible Genotypes: AA, Aa, aa
Ocho Nueve's Genotype: aa

Belly Button Types. (Single Allele Trait)
Possible Phenotypes: Regular Belly Button (Dominate) vs. Pouch Belly Button (Recessive)
Possible Genotypes: PP, Pp, pp
Ocho Nueve's Genotype: pp

Leg Shapes. (Single Allele Trait)
Possible Phenotypes: Toothpick Legs (Dominate) vs. Popsicle Stick Legs (Recessive)
Possible Genotypes: TT, Tt, tt
Ocho Nueve's Genotype: TT

Eye Colors. (Codominant Trait)
Possible Phenotypes: Red Eyes, Creme Eyes, One Red and One Creme Eye
Possible Genotypes: BB (Red Eyes), Bb (Creme Eye and Red Eye), bb (Creme Eyes)
Ocho Nueve's Genotype: Bb

Wing Types. (Multiple Allele Trait)
Possible Phenotypes: Bat Wings, Fly Wings, Hummingbird Wings
Possible Genotypes: bb, bf, bh, fh (Bat Wings) ff (Fly Wings) hh (Hummingbird Wings)
Ocho Nueve's Genotype: bf

Nose Types. (Sex Linked Trait)
Possible Phenotypes: Fluffy Nose replaces Flat Nose when the trait is displayed.
Possible Genotypes: X'Y, XY
Ocho Nueve's Genotype: X'Y

Body Color. (Incomplete Dominance)
Possible Phenotypes: Yellow Body, Blue Body, Green Body
Possible Genotypes: YY (Yellow), yy (Blue), Yy (Green)
Ocho Nueve's Genotype: Yy

Ocho Nueve has curved antennae, a pouched belly button, toothpick legs, multi-colored eyes, bat wings, a fluffy nose, and a green colored body. So pretty much he's a beast.

Sunday, February 21, 2010

Innocence :: Ocho Nueve's DNA strand

gacggacttcatcgatcgatcgatcgTATctagcatgctagctagcatga
-------------------------------------------------------------
ctgcctgaagtagctagctagctagcATAgatcgtacgatcgatcgtact

Innocent, as suspected. They probably just mistook Ocho Nueve as Ex Ocho Nueve. Their name's are awfully similar...

Saturday, February 20, 2010

Ocho Nueve Marries Senora Numero Uno

Here's a sample pedigree for the next 10 generations of poco Ocho Nueve.

Next we have a dihybrid cross using traits for leg shapes and antenna types. (I know, Senora Numera Uno's leg shape doesn't fit that of the pedigree, but bear with me here.)

Thursday, February 18, 2010

What Just Happened??

Need help better understanding exactly what I just did?? Try these sample questions.

1. Ocho Nueve almost married a chica by the name of Nueve Cero, but she left him for another man. Pretend they did get married. Cross Ocho Nueve's SS genotyped antennae with Nueve Cero's Ss genotyped antennae.

2. Pretend Ocho Nueve's little chico named Sinco Duo and Ocho Nueve's little nina named Quatro Tres got married. Yes, incest happens sometimes. Cross their antenna types.

3. Is it possible for Ocho Nueve and Senora Numero Uno to have a child with straight antennae?? Why or why not??

BONUS QUESTION!! If you were paying attention to names (Not counting Senora Numero Uno), they're all numbers in Spanish. Can you figure out what Ocho Nueve, Tres Quatro, Sinco Duo, Quatro Tres, Ex Ocho Nueve, and Nueve Cero all have in common?? What do each of them stand for?? If you knew me really well, you'd probably be able to figure this out.

Wednesday, February 17, 2010

Answer to the Bonus Question

What do Ocho Nueve, Tres Quatro, Sinco Duo, Quatro Tres, Nueve Cero and Ex Ocho Nueve all have in common?? What do each of them stand for??

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With the exception of Ex Ocho Nueve, they're my 5 favorite Carolina Panthers player. Ocho Nueve is #89 Steve Smith, Tres Quatro is #34 DeAngelo Williams, Sinco Duo is #52 Jon Beason, Quatro Tres is #43 Chris Harris, and Nueve Cero is #90 Julius Peppers.

Julius Peppers is leaving the Panthers this offseason, which is why I chose him as the wife who left Ocho Nueve. Makes sense, doesn't it??

Ex Ocho Nueve is former #89 Rae Carruth. I had him as the convict who's DNA strand was found at the crime scene because he was involved in the killing of his wife.

Senora Numero Uno just means Lady Number One, meaning she is Ocho Nueve's #1 lady.

So yeah, that's what the names mean in case you were wondering.